Energized with Dr. Mariza

“What if the exhaustion, brain fog, low libido, and metabolic changes women experience in midlife are actually rooted in a deeper cellular energy crisis?”

In this episode, Dr. Mariza sits down with Dr. Andrew Salzman — physician, inventor, biochemical engineer, and Chief Scientific Officer of Wonderfeel — to unpack the powerful connection between NAD, mitochondrial health, inflammation, ovarian aging, gut integrity, nitric oxide, and the dramatic energy shifts women experience during perimenopause and menopause.

Dr. Salzman explains why menopause represents a major biological inflection point for women and how declining NAD levels may be contributing to fatigue, brain fog, poor recovery, metabolic dysfunction, sleep issues, reduced stress resilience, cardiovascular changes, and shifts in sexual health.

Together, they explore the evolutionary role of menopause, why ovarian senescence accelerates aging pathways, how inflammation and the enzyme CD38 rapidly deplete NAD stores, and why the gut microbiome may be one of the biggest drivers of inflammation and energy decline in modern women.

They also dive into nitric oxide production, cardiovascular health, the brain’s dependence on NAD for sleep and cognitive function, and why ingredients like NMN and creatine are gaining attention for supporting healthy aging and resilience in midlife.

If you’ve ever looked in the mirror and thought, “I don’t feel like myself anymore,” this conversation will help connect the dots between your symptoms, your mitochondria, and your long-term vitality.

ANDREW SALZMAN

Dr. Andrew Salzman is a physician, inventor, biochemical engineer, and the Chief Scientific Officer of Wonderfeel. With more than 30 years of experience in drug discovery and development, over 170 scientific publications, and more than 50 patents, Dr. Salzman has spent decades studying aging biology, inflammation, cellular resilience, nitric oxide signaling, and mitochondrial health

IN THIS EPISODE

Why menopause is a major biological inflection point for women

How declining NAD levels impact energy, metabolism, sleep, and brain function

Why CD38 accelerates inflammation and NAD depletion during aging

The surprising connection between gut health, inflammation, and menopause symptoms

How estrogen decline contributes to leaky gut and systemic inflammation

Why nitric oxide is essential for circulation, libido, cardiovascular health, and cognition

The role of NAD in circadian rhythm, sleep quality, and stress resilience

Why NMN and creatine are gaining attention for healthy aging and vitality

QUOTES“Menopause will happen, but the question is: how do we maintain vibrancy and resilience through it?”

“NAD is the common currency that drives energy throughout the body.”

“The gut is the foundational driver of inflammation as we age.”

“Without NADPH, you don’t have nitric oxide production.”

RESOURCES MENTIONED

Subscribe and Save $15 on Wonderfeel Youngr™ NMN:

https://tidd.ly/4rPnckS

Use code ENERGIZED and get 30% off on your first BATCH order

https://hellobatch.com/ENERGIZED

Order my newest book: The Perimenopause Revolution

https://peri-revolution.com/

Wonderfeel Website

Wonderfeel Instagram

Wonderfeel YouTube

RELATED EPISODES 

741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

691: The Fertility Crisis No One Talks About: Why Your Health Today Impacts Future Generations with Dr. Ann Shippy

717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan

“What if the life you worked so hard to build is also the thing quietly burning you out?”

In this episode, Dr. Mariza sits down with Brooke Taylor to unpack the hidden emotional patterns driving burnout, overachievement, perfectionism, and chronic stress in high-performing women.

Brooke shares her deeply personal story—from climbing the corporate ladder at Google while battling addiction, burnout, and health issues—to ultimately discovering what she now calls the “Success Wound.” Together, they explore how so many women unconsciously tie their worth, safety, belonging, and identity to achievement… until their body can no longer sustain the pressure.

They dive into the emotional roots of over-functioning, the nervous system impact of constantly “doing,” and why midlife often becomes the moment women can no longer outrun themselves. Brooke also shares practical tools to identify your own success wound patterns, regulate your nervous system, reconnect to your true self, and move from manic ambition into aligned ambition.

If you’ve ever felt exhausted despite accomplishing so much… if you’ve struggled to slow down, feel present, or believe you’re enough without constantly proving yourself… this conversation will hit deeply.

BROOKE TAYLOR

Brooke Taylor is a transformational career coach, speaker, and former Google marketing lead who has helped over 5,000 high-performing women redefine success on their own terms. After experiencing burnout, addiction, and deep emotional reckoning in her own life, Brooke developed the framework she now calls the “Success Wound” to help women break free from overachievement patterns and reconnect to fulfillment, purpose, and self-worth.

IN THIS EPISODE

What the “Success Wound” actually is—and how it develops

Why high-achieving women often tie worthiness to productivity

The hidden connection between burnout, perfectionism, and chronic stress

How childhood conditioning shapes our relationship with achievement

The 5 success wound archetypes: Grinder, Pleaser, Hider, Seeker, and Work Hard/Play Hard

Why perimenopause can intensify emotional and nervous system burnout

The difference between manic ambition and aligned ambition

Practical tools to regulate your nervous system and reconnect to your true self

Why healing your success wound is lifelong work—not a quick fix

QUOTES“The more that I succeeded, the more love, belonging, and approval I would get.”

“We don’t rise to the level of our confidence. We fall to the level of our self-worth.”

“You are not working from the most powerful part of yourself when you’re working from fear.”

“There is nothing wrong with your ambition. It’s the way your worth became tied to it that needs healing.”

RESOURCES MENTIONED

Grab Brooke’s new book The Success Wound

https://amzn.to/3RoWBOC

Use code ENERGIZED and get 10% off on your Troscription Order

http://troscriptions.com/ENERGIZED

Order my new book The Perimenopause Revolution

https://peri-revolution.com/

Brooke Taylor Website

Brooke Taylor Instagram

Brooke Taylor Tiktok

RELATED EPISODES 

717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

733: Why We’re Still Exhausted in the Age of “Evidence-Based” Everything with Shawn Stevenson

728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It

“What if your body isn’t failing you… but asking for a different kind of support?”

In this episode, Dr. Mariza sits down with Mickey Trescott to unpack the powerful connection between inflammation, autoimmune disease, gut health, and perimenopause.

Together, they explore why so many women are dismissed when labs look “normal” despite debilitating symptoms like fatigue, bloating, brain fog, joint pain, skin issues, and weight resistance. Mickey shares her personal journey with Hashimoto’s, celiac disease, and autoimmune recovery—and how the Autoimmune Protocol (AIP) became a transformative tool for reducing inflammation and helping millions feel better in their bodies.

They also dive into the evolution of AIP over the last 15 years, the newest research validating its effectiveness, and why perimenopause often becomes an inflammatory inflection point where hidden symptoms suddenly rise to the surface.

If you’ve been struggling with chronic inflammation, unexplained symptoms, or feeling dismissed by conventional medicine, this conversation will help you connect the dots—and give you practical hope moving forward.

MICKEY TRESCOTT

Mickey Trescott is a nutritional therapy practitioner, cookbook author, and co-creator of the Autoimmune Protocol (AIP). After being diagnosed with Hashimoto’s thyroiditis and celiac disease in her twenties, she dedicated her work to helping people navigate autoimmune disease through nutrition, lifestyle medicine, and inflammation support. She has helped shape the modern AIP movement and trained hundreds of healthcare practitioners around the world.

IN THIS EPISODE

Why autoimmune disease impacts women at significantly higher rates

How inflammation often worsens during perimenopause and menopause

The connection between gut health, food sensitivities, and immune regulation

Why “normal labs” don’t always reflect how women actually feel

The science and research behind the Autoimmune Protocol (AIP)

The difference between Core AIP and the newer Modified AIP approach

Why food reintroductions and personalization are key for long-term healing

QUOTES“Your body is not working against you. It’s asking for a different level of support.”

“Three out of every four-ish people get clinical improvement from doing an elimination diet when you have autoimmune disease.”

“When hormones begin to shift, the body becomes far less tolerant of underlying inflammation.”

RESOURCES MENTIONED

Order my new book: The Perimenopause Revolution

https://peri-revolution.com/

Use code ENERGIZED and get 30% off on your first BATCH order

http://hellobatch.com/ENERGIZED

Grab Mickey’s new AIP book 

https://theautoimmuneprotocol.com/

Visit Autoimmune Wellness Website

Autoimmune Wellness Instagram

Mickey Trescott Instagram

Mickey Trescott Facebook

Mickey Trescott Youtube

RELATED EPISODES 

747: The Silent Shift: Why Perimenopause Changes Everything

717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

741: Estrogen, Gut Health, and Metabolism with Siobhan Mitchell

728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It

“Perimenopause is more than just hot flashes and mood swings—it’s a biological inflection point.”

In this solo episode, Dr. Mariza discusses the deeper, often overlooked changes happening during perimenopause and menopause. It’s more than a reproductive shift; it’s a systemic change affecting the brain, metabolism, hormones, mitochondria, gut health, and more.

Dr. Mariza delves into the silent shift that many women experience—feeling exhausted, stressed, and unproductive despite their best efforts. She explains how perimenopause accelerates aging processes, and why early intervention is key to reducing long-term health risks and preserving vitality.

This episode focuses on actionable steps you can take to support your body during this critical transition—from stabilizing blood sugar and building muscle to optimizing sleep and protecting your brain.

If you’ve been feeling “off” but can’t explain why, this episode is a must-listen.

Be sure to tune in!

IN THIS EPISODE

Why perimenopause is a biological and metabolic inflection point

The connection between hormonal fluctuations, mitochondria, and energy

How perimenopause accelerates aging and increases risk for chronic diseases

Why "just pushing through" is not the solution for midlife women

The importance of early intervention for better long-term health outcomes

Simple strategies for building energy, optimizing brain function, and protecting your future health

How stabilizing blood sugar, improving muscle mass, and prioritizing sleep can reduce inflammation and support resilience

QUOTES“Perimenopause is more than just skipped periods or hot flashes. It’s a shift in every system of the body.”

“You deserve so much better than being told to just survive this season.”

“The moment to intervene is now—not when your health has deteriorated.”

RESOURCES MENTIONED

Order my newest book: The Perimenopause Revolution

https://peri-revolution.com/

Use code ENERGIZED and get 10% off on your Troscription Order

http://troscriptions.com/ENERGIZED

Use code DRMARIZA and get 10% off on your Womeness Order

https://www.womaness.com/DRMARIZA

Check out the Morning Metabolic Ignition Method for better energy and resilience

RELATED EPISODES 

744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now

717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It

741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

“Is your nervous system stuck in overdrive?”

In this episode, Dr. Mariza sits down with Jenna Free, a counselor specializing in ADHD and nervous system regulation, to discuss why so many women in midlife feel overwhelmed, scattered, and exhausted despite their best efforts to stay organized.

Together, they explore how the nervous system gets stuck in a chronic fight-or-flight state, the role of dysregulation in ADHD symptoms, and why traditional productivity hacks simply don’t work when your nervous system is running on empty.

Jenna breaks down her approach to resetting the nervous system and explains how small, consistent changes can lead to massive improvements in mental clarity, energy, and overall well-being.

This conversation offers new insights on how to break free from the cycle of rushing, crashing, and feeling burned out—and provides tangible steps to reclaim control over your brain and nervous system.

JENNA FREE

Jenna Free is a counselor specializing in ADHD, nervous system regulation, and mindfulness practices. She is passionate about helping women overcome the chaos of constant overwhelm and hypervigilance by teaching them how to regulate their nervous systems and achieve sustainable productivity. Jenna is the author of The Simple Guide to ADHD Regulation and offers support to those struggling with ADHD and chronic stress

IN THIS EPISODE

How a dysregulated nervous system contributes to ADHD-like symptoms in midlife

The link between survival mode (fight or flight) and chronic overwhelm

Why traditional productivity hacks fail when your nervous system is stuck

Practical tips to help interrupt dysregulation and shift into a more balanced state

The importance of slowing down and creating space for mindful action

How to reframe beliefs and thoughts to support nervous system regulation

Why a regulated nervous system leads to more sustainable energy and better overall functioning

QUOTES“Being in survival mode is a primal mechanism, but it’s not meant to be how we live in 2026.”

“If you believe that being frantic and rushed is the way to be successful, you will never change.”

“Regulation work isn’t about feeling nice—it’s about functioning better.”

RESOURCES MENTIONED

Use code ENERGIZED and get 10% off on your MitoQ Order

https://www.mitoq.com/energized 

Order The Simple Guide to ADHD Regulation

https://www.jennafree.com/book

⁠Order my newest book: The Perimenopause Revolution⁠⁠Jenna Free

https://peri-revolution.com/

Jenna Free Website

https://www.jennafree.com/

Jenna Free Instagram

Jenna Free Youtube

RELATED EPISODES 

744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now

728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It

717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

693: Tired All the Time? It Might Be Hidden Problems With Your Mitochondria with Siobhan Mitchell