Health and Medicine (Audio)

Heart regeneration faces two connected challenges: replacing lost muscle and keeping transplanted cells safe and accepted by the body. Charles Murry, M.D., Ph.D., of USC explains why the adult heart heals major cardiomyocyte loss with scar tissue rather than new muscle, leading to progressive heart failure. Murry describes how stem cell derived cardiomyocytes can be manufactured at scale, transplanted into injured hearts, and tested for function in animal models. He also examines major barriers, including graft related arrhythmias, calcium handling stress, immune rejection, and the need for practical immunosuppression or immune edited cells. By connecting cell manufacturing, electrophysiology, immunology, and clinical trial planning, this research shows why heart regeneration is difficult and why careful translation matters for patients with severe heart injury. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40853]

Fertility health affects conception and reproductive planning in important ways. Jennifer Ashby, DAOM, and Maren Shapiro, MD, explain how East Asian medicine principles and daily habits shape fertility optimization. Ashby examines Jing, Blood, Qi, Yin/Yang balance, and stress, while Shapiro examines sleep, nutrition, exercise, supplements, timing intercourse, and when to seek additional support, helping clarify how the body can be supported before pregnancy. This work helps explain conception readiness and points toward practical strategies for reproductive health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41546]

As part of the 2026 Developmental Disabilities Conference, Dr. Paul Glassman, Professor and Associate Dean for Research and Community Engagement, College of Dental Medicine, California Northstate University, discusses dental care for people with developmental disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41462]

As part of the 2026 Developmental Disabilities Conference, Kavitha Murthi,Assistant Professor, Rutgers University, discusses occupational therapy for autistic people.

Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41463]

Hematopoietic stem cells make blood across the lifespan, but they do not all behave the same way. Stephanie Xie, Ph.D., Scientist at Princess Margaret Cancer Centre, University of Toronto, examines how these rare cells self-renew, differentiate, and respond to inflammatory stress, asking whether differences in the stem cell pool help explain why aging affects people so differently. Xie identifies two hematopoietic stem cell subsets, including one that retains inflammatory memory after stress recovery, and connects this state to aging, clonal hematopoiesis, sickle cell disease, post-COVID recovery, and mortality risk markers in blood. Her research also raises questions about whether targeting the inflammatory environment, including through GLP-1 receptor agonists or metformin, could help mitigate clonal hematopoiesis. Understanding these patterns could clarify how inflammation shapes blood production, cancer risk, and immune health over time. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41406]