This episode explores Alzheimer’s from prevention to treatment. Alongside Laura Forcano (HMRIB) and Oriol Grau-Rivera (FPM-BBRC-HMRIB), our two experts, we look at lifestyle interventions designed to slow cognitive decline, alongside efforts to detect early cognitive changes and test how new trials can be implemented in clinics. The conversation also covers new drugs targeting amyloid and tau, their promise and risks, and the importance of including low socio-economic groups in dementia research. Beyond the science, we discuss how communication and language can empower the public and fight stigma around dementia.‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
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35:21
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35:21
Mutations
This episode dives into the world of genetics and mutations. We’re joined by two experts: Marc de Manuel (IBE) studying the mechanisms and evolutionary variation of mutations, and Donate Weghorn (CRG) developing computational models to predict mutation probability. Together, they shed light on cancer, inherited mutations across families, and the curious Peto’s paradox—why bigger, longer-lived animals aren’t necessarily more prone to cancer. We also step outside the lab to discuss careers in research: short-term versus tenure-track contracts for early-stage PIs, and whether institutions truly value the right qualities when it comes to promotion.‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
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39:21
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39:21
Can diet affect mental health?
In this episode, we’re exploring how what we eat shapes how we feel. Our guests—Camille Lassale (ISGlobal) a Principal Investigator and Gabriela Lugon (HMRIB) a research clinician—share their perspectives on diets linked to mental health, the challenges of studying this connection, and why investing in these approaches could benefit both society and the economy. They also walk us through real projects that highlight just how important nutrition is for mental wellbeing. In our transversal discussion, we turn to the realities of academia, tackling the hurdles and barriers that researchers face as they build their careers.‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
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37:30
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37:30
Starting out in cancer research
We’re kicking off our first episode with a deep dive into cancer research, joined by two PhD students from the PRBB: Heleen Jungen (EMBL Barcelona) & Júlia Urgel (CRG-MELIS UPF). They share their current work on metabolism in non-small cell lung cancer and the progression of pulmonary neuroendocrine lung cancer; while also looking ahead to how personalized medicine could shape future treatments. Beyond the science, we explore their different paths into research, the realities of finding a PhD, and what life in academia feels like when you’re just starting out. ‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
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39:52
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39:52
Unravelling the living cell: What are we missing?
Since its discovery, our understanding of cells has evolved from simple structures to complex systems of organelles, proteins, and genetic material that interact in sophisticated ways. However, our understanding is far from complete with many cellular processes, such as signal transduction, metabolic networks and inter-cellular communication remaining a mystery! So, What are we still missing in our understanding of the living cell? To help us break it all down, we’re joined by two leading experts, Alfonso Martínez-Arias from MELIS-UPF and Vikas Trivedi from EMBL Barcelona, for a thought-provoking conversation on where the field stands today. We’ll dive into the power of multidisciplinary approaches, challenge the current research paradigms, and wrestle with the deeper question: What does it truly mean to understand a cell? Plus, we’ll turn our focus to an equally important issue: what makes for great research supervision? Our guests share their personal insights, and we ask the PRBB community for their take on this transversal topic.‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
Science with a view is the PRBB podcast where Chris George, proposal developer at HMRIB, invites two researchers to delve into their areas of expertise while addressing critical themes in research culture. Each episode also features the “PRBB voices” segment, enriching the discussion with a variety of perspectives and opinions. ‘Science With a View’ a PRBB production:Script & presenter: Chris GeorgeEditing: Inés FuentesRecording: Jordi Blanco & Rosa CamachoPost-production: Teo GrimaltTheme tune: Liam Colomer (voice-over, Alix Musset)
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