Best Natural Alternatives for Common Prescription Drugs
What if your fatigue, anxiety, or brain fog isn’t from your condition—but from the meds you’re taking?
In this episode, Dr. Josh Axe uncovers how common medications can deplete key nutrients, trigger side effects, and keep you from true healing. Learn what’s really going on—and the natural alternatives that work.
The top nutrient-depleting drugs and what they do to your body.
Symptoms that are actually caused by medications (not your illness).
Natural options for pain, anxiety, reflux, high cholesterol, and more.
How to heal by getting to the root cause—not masking it.
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Links:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8579431/
https://www.cdc.gov/nchs/data/databriefs/db470.pdf
https://www.uspharmacist.com/article/americans-take-prescriptions-a-large-portion-of-their-lives
https://ssri.psu.edu/news/americans-will-spend-half-their-lives-taking-prescription-drugs-study-finds
https://pharmacy.msu.edu/resources/nutrient-depletion-is-an-often-overlooked-side-effect-of-some-medications
https://www.cdc.gov/nchs/data/nhsr/nhsr213.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC4573453/
https://news.gallup.com/poll/654425/americans-say-overweight-slim-down.aspx
https://gi.org/topics/irritable-bowel-syndrome/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6007725/
https://www.nhlbi.nih.gov/health/sleep-deprivation
https://www.jwatch.org/na55225/2022/08/16/antidepressants-work-only-small-subset-patients
https://pubmed.ncbi.nlm.nih.gov/31475623/
https://pubmed.ncbi.nlm.nih.gov/26424423/
https://pubmed.ncbi.nlm.nih.gov/26424423/
https://pubmed.ncbi.nlm.nih.gov/30564123/
https://pmc.ncbi.nlm.nih.gov/articles/PMC4757677/
https://www.uclahealth.org/news/article/ask-the-doctors-not-much-scientific-evidence-to-support-use-of-coq10-for-pain
https://www.europeanreview.org/article/4579
https://www.sciencedirect.com/science/article/abs/pii/S0031395509000807?via%3Dihub
https://pmc.ncbi.nlm.nih.gov/articles/PMC5126440/
https://www.ncbi.nlm.nih.gov/books/NBK557385/
https://pubmed.ncbi.nlm.nih.gov/36464072/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8395812/
https://www.medrxiv.org/content/10.1101/2025.02.20.25322455v1.full
https://jamanetwork.com/journals/jama/fullarticle/2787541
https://www.ncbi.nlm.nih.gov/books/NBK430882/
https://pubmed.ncbi.nlm.nih.gov/35685421/
https://www.nhs.uk/contraception/methods-of-contraception/natural-family-planning/
https://www.sciencedirect.com/science/article/abs/pii/S0049017208001339?via%3Dihub
https://www.arthritis.org/health-wellness/healthy-living/nutrition/anti-inflammatory/turmeric-wont-help-arthritis
https://www.ncbi.nlm.nih.gov/books/NBK547742/
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1:00:05
Why Men and Women Shouldn’t Eat the Same Way
Did you know men and women can respond differently to the same diet, supplement, or workout—simply because of biology?
In this episode, Dr. Josh Axe dives deep into the unique nutritional, hormonal, and emotional needs of men and women. From PMS to prostate health, fertility to fasting, this is the guide to understanding how gender shapes our health—and what to do about it.
The key nutrient deficiencies men and women face—and why they differ.
How hormones, cycles, and life stages shift nutritional needs in women.
Why intermittent fasting affects women and men differently.
What sleep and emotional stress do to hormones across sexes.
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Links:
https://recreation.gsu.edu/2023/09/28/ways-to-support-females-hormones-through-nutrition/
https://www.nature.com/articles/nri.2016.90
https://pmc.ncbi.nlm.nih.gov/articles/PMC10031253
https://www.nature.com/articles/s41598-018-32647-0
https://pmc.ncbi.nlm.nih.gov/articles/PMC9710417/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6010824/
https://umiamihealth.org/treatments-and-services/uhealth-comprehensive-women%E2%80%99s-health-alliance/women's-services/nutrition-services/common-vitamin-deficiencies-for-us-womenhttps://ods.od.nih.gov/factsheets/Iron-HealthProfessional/
https://www.bonehealthandosteoporosis.org/patients/treatment/calciumvitamin-d/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8877546/
https://lpi.oregonstate.edu/mic/micronutrient-inadequacies/overview
https://www.cdc.gov/nutrition-report/about/index.html
https://hsph.harvard.edu/news/billions-worldwide-consume-inadequate-levels-of-micronutrients-critical-to-human-health/
https://www.tandfonline.com/doi/10.1186/s12970-021-00412-w?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed#d1e502
https://pubmed.ncbi.nlm.nih.gov/39830337/
https://www.mountsinai.org/health-library/condition/premenstrual-syndrome
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00276-6/fulltext
https://archive.cdc.gov/www_cdc_gov/diabetes/library/reports/reportcard/national-state-diabetes-trends.html
https://www.mdpi.com/1660-4601/18/24/13213
https://pmc.ncbi.nlm.nih.gov/articles/PMC4164903/
https://pmc.ncbi.nlm.nih.gov/articles/PMC3328995/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5613977/
https://womenshealth.gov/a-z-topics/insomnia
https://womenshealth.gov/a-z-topics/thyroid-disease
https://www.medstarhealth.org/blog/heart-disease-men
https://www.cancer.org/cancer/risk-prevention/understanding-cancer-risk/cancer-facts/cancer-facts-for-men.html
https://www.cdc.gov/nchs/products/databriefs/db516.htm
https://www.issaonline.com/blog/post/this-hot-diet-trend-is-not-recommended-for-women
https://health.clevelandclinic.org/intermittent-fasting-for-women
https://www.mayoclinic.org/diseases-conditions/sleep-apnea/symptoms-causes/syc-20377631
https://pmc.ncbi.nlm.nih.gov/articles/PMC5831910/
https://longevity.stanford.edu/lifestyle-medicine-2-relationships/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6125010/
https://pubmed.ncbi.nlm.nih.gov/28463088/
https://www.psychologytoday.com/us/blog/so-happy-together/201712/men-vs-women-and-emotional-support
https://www.psychiatry.org/news-room/apa-blogs/men-women-and-differing-responses-to-stress
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32:38
This Nutritional Therapy is 10x More Effective Than Supplements
What if your supplements aren’t working—because your gut can’t absorb them?
In this episode, Dr. Josh Axe breaks down the science and safety behind Vitamin IV Therapy, the growing trend used by celebrities, CEOs, and health pros alike to boost energy, immunity, and brainpower.
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Links:
https://www.americaniv.com/iv-therapy-vitamins-benefits-costs-and-side-effects/
https://www.msdmanuals.com/home/special-subjects/dietary-supplements-and-vitamins/intravenous-vitamin-therapy-myers-cocktail
https://www.grandviewresearch.com/industry-analysis/north-america-intravenous-iv-hydration-therapy-market-report
https://pmc.ncbi.nlm.nih.gov/articles/PMC10855962/
https://mcpress.mayoclinic.org/living-well/iv-vitamin-therapy-understanding-the-lack-of-proven-benefit-and-potential-risks-of-this-health-fad/
https://www.cedars-sinai.org/blog/iv-vitamin-therapy.html
https://pubmed.ncbi.nlm.nih.gov/33523616/
https://ods.od.nih.gov/factsheets/PrimaryMitochondrialDisorders-HealthProfessional/
https://pmc.ncbi.nlm.nih.gov/articles/PMC2894814/
https://www.mdpi.com/2072-6643/9/11/1211
https://pubmed.ncbi.nlm.nih.gov/33652579/
https://link.springer.com/article/10.1007/s00394-014-0706-z
https://www.sciencedirect.com/science/article/pii/S2161831322004112?via%3Dihub
https://pmc.ncbi.nlm.nih.gov/articles/PMC5719794/
https://linkinghub.elsevier.com/retrieve/pii/S0003-4975(24)01029-4
https://pubmed.ncbi.nlm.nih.gov/37971292/
https://pmc.ncbi.nlm.nih.gov/articles/PMC9662251/
https://journal.chestnet.org/article/S0012-3692(22)03890-9/fulltext
https://my.clevelandclinic.org/health/drugs/20379-magnesium-sulfate-injection
https://reference.medscape.com/drug/mgso4-magnesium-sulfate-344444
https://www.drugs.com/pro/selenium-injection.html
https://pubmed.ncbi.nlm.nih.gov/19874951/
https://pmc.ncbi.nlm.nih.gov/articles/PMC10817270/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5240054/
https://pmc.ncbi.nlm.nih.gov/articles/PMC9450039/
https://pubmed.ncbi.nlm.nih.gov/36726625/
https://pubmed.ncbi.nlm.nih.gov/26371950/
https://onlinelibrary.wiley.com/doi/10.1002/mnfr.201200636
https://dtb.bmj.com/content/61/10/151.long
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42:49
Modern Medicine Was Built on Lies (What Big Pharma WON’T TELL YOU)
Did you know Americans now spend over $400 billion a year on prescriptions—yet chronic disease is only rising?
In this episode, Dr. Josh Axe uncovers the hidden history and ongoing influence of Big Pharma, revealing how natural medicine was pushed aside—and what you can do to reclaim your health.
How the Flexner Report and Rockefeller shaped a drug-first medical system.
Why 69% of U.S. adults take at least one medication—and 25% take four or more.
The financial and political power of pharma giants, from Fauci to Pfizer.
Why so many “diagnoses” today are just symptoms of a deeper imbalance.
How the food system feeds illness—and pharma profits from the fallout.
The root-cause tools of functional medicine that actually promote healing.
Tune in to discover the truth about pharmaceuticals, the future of functional medicine, and how you can support your body naturally—without relying on daily prescriptions.
#RootCauseHealing #BigPharmaExposed #FunctionalMedicine
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Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually.
Every Wednesday, you'll get:
Holistic health news & life-hacks from a biblical world view
Powerful free resources including classes, Q&As, and guides from Dr. Axe
The latest episodes of The Dr. Josh Axe Show
Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe
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Links:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3178858/
https://www.consumerreports.org/prescription-drugs/too-many-meds-americas-love-affair-with-prescription-medication/
https://www.statista.com/outlook/hmo/pharmaceuticals/worldwide
https://www.biospace.com/u-s-pharmaceutical-market-size-to-reach-usd-1-093-79-billion-by-2033
https://www.hrsa.gov/opa/updates/2023-340b-covered-entity-purchases
https://www.npr.org/2025/04/24/nx-s1-5374372/millions-of-american-kids-have-an-adhd-diagnosis-is-their-treatment-effective
https://www.cnn.com/2023/04/18/health/teen-misuse-adhd-meds-wellness/index.html
https://www.cdc.gov/nchs/products/databriefs/db388.htm
https://www.aafp.org/pubs/afp/issues/2019/1215/p742.html
https://pmc.ncbi.nlm.nih.gov/articles/PMC4859526/\
https://www.ncbi.nlm.nih.gov/books/NBK532953/
https://hpi.georgetown.edu/rxdrugs/
https://www.cdc.gov/nchs/products/databriefs/db347.htm
https://www.ncbi.nlm.nih.gov/books/NBK430655/
https://www.investopedia.com/articles/stocks/09/corporate-kleptocracy-rjr-nabisco.asp
https://www.cdc.gov/museum/pdf/cdcm-pha-stem-uncovering-the-opioid-epidemic-lesson.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC2034715/
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00418
https://www.nami.org/advocacy/policy-priorities/improving-health/mental-health-in-schools/
https://www.cms.gov/priorities/key-initiatives/open-payments
https://pmc.ncbi.nlm.nih.gov/articles/PMC3778453/
https://www.pharmavoice.com/news/big-pharma-campaign-election-pac-donations/731124/
https://www.fiercepharma.com/pharma/fda-blocks-biopharma-employees-serving-advisory-committees
https://pmc.ncbi.nlm.nih.gov/articles/PMC10830426/
https://weillcornell.org/news/america%E2%80%99s-loneliness-epidemic-what-is-to-be-done
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43:04
This Is What’s REALLY Causing Inflammation (And How to Fix It) | Dr. Gundry
What if inflammation isn’t just a symptom, but the real root of nearly every chronic disease?
In this episode, Dr. Josh Axe sits down with bestselling author and cardiologist Dr. Steven Gundry to reveal what’s actually driving inflammation, from leaky gut and mitochondrial dysfunction to hidden environmental triggers. You’ll learn the science behind why your body feels like it’s constantly under attack and how to reverse it naturally.
Dr. Gundry shares his top strategies to heal the gut, support mitochondrial health, and calm the immune system using simple tools like vitamin D3, infrared saunas, fermented foods, and more.
You’ll Learn:
The true root cause of inflammation (and why most people miss it)
Why healing your gut is the key to reversing disease
How red light, heat therapy & vitamin D restore your energy
Foods Dr. Gundry recommends for gut and mitochondrial health
This episode was made possible by Sunlighten. Use code AXE to save up to $1,400 on your purchase.
Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel.
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Follow Dr. Steven Gundry
Instagram
Facebook
X
Website
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Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually.
Every Wednesday, you'll get: Holistic health news & life-hacks from a biblical world view
Powerful free resources including classes, Q&As, and guides from Dr. Axe
The latest episodes of The Dr. Josh Axe Show
Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe
------
Links:
Check out Dr. Steven Gundry’s latest book, The Gut-Brain Paradox → https://www.amazon.com/Gut-Brain-Paradox-Improve-Reverse-Microbiome/dp/0062911805
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Join Dr. Josh Axe, founder of draxe.com, Ancient Nutrition, and The Health Institute, as he explores the intersections of natural health, personal growth, and psychology. Each episode dives into the latest in natural medicine, nutrition, emotional resilience, and spiritual growth, alongside strategies for mindset, and living a purpose-driven life. With expert insights, practical advice, and inspiring stories, Dr. Axe empowers listeners to elevate their health and maximize their potential in every aspect of life.