"The Cognitive Revolution" | AI Builders, Researchers, and Live Player Analysis

Karan Singhal, Head of Health AI at OpenAI, explains how ChatGPT Health is achieving attending-physician-level performance and already serving hundreds of millions of users. He details how OpenAI works with over 250 doctors, built the 49,000-criteria HealthBench evaluation, and ran one of the first randomized trials of AI copilots in clinical care. The conversation explores privacy and safety safeguards, medical multimodality, N-of-1 treatment plans, and how AI could become a standard part of global medical practice.

Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot
LINKS:
modeling human wellness
Sponsors:

Claude:
Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr

Serval:
Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week 4 at https://serval.com/cognitive

Framer:
Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive

Tasklet:
Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

CHAPTERS:

(00:00) About the Episode

(06:11) Cancer story and mission

(11:46) Designing safe health AI (Part 1)

(17:49) Sponsors: Claude | Serval

(21:09) Designing safe health AI (Part 2)

(26:48) Uncertainty, HealthBench and robustness (Part 1)

(30:23) Sponsors: Framer | Tasklet

(32:50) Uncertainty, HealthBench and robustness (Part 2)

(38:11) Chain-of-thought and evaluation

(46:49) Real-world performance and frontiers

(55:35) Multimodal data and science

(01:05:36) Personalization, privacy and monitoring

(01:15:47) Models, data and incentives

(01:29:31) Doctor adoption and workflows

(01:38:13) Scalable oversight and alignment

(01:51:06) Move 37 and future

(02:00:50) Episode Outro

(02:03:06) Outro

PRODUCED BY:

https://aipodcast.ing

Olive Song from MiniMax shares how her team trains the M series frontier open-weight models using reinforcement learning, tight product feedback loops, and systematic environment perturbations. This crossover episode weaves together her AI Engineer Conference talk and an in-depth interview from the Inference podcast. Listeners will learn about interleaved thinking for long-horizon agentic tasks, fighting reward hacking, and why they moved RL training to FP32 precision. Olive also offers a candid look at debugging real-world LLM failures and how MiniMax uses AI agents to track the fast-moving AI landscape.

Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot
LINKS:
Conference Talk (AI Engineer, Dec 2025) – https://www.youtube.com/watch?v=lY1iFbDPRlwInterview (Turing Post, Jan 2026) – https://www.youtube.com/watch?v=GkUMqWeHn40
Sponsors:

Claude:
Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr

Tasklet:
Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

CHAPTERS:

(00:00) About the Episode

(04:15) Minimax M2 presentation (Part 1)

(17:59) Sponsors: Claude | Tasklet

(21:22) Minimax M2 presentation (Part 2)

(21:26) Research life and culture

(26:27) Alignment, safety and feedback

(32:01) Long-horizon coding agents

(35:57) Open models and evaluation

(43:29) M2.2 and researcher goals

(48:16) Continual learning and AGI

(52:58) Closing musical summary

(55:49) Outro

PRODUCED BY:

https://aipodcast.ing

SOCIAL LINKS:

Website: https://www.cognitiverevolution.ai

Twitter (Podcast): https://x.com/cogrev_podcast

Twitter (Nathan): https://x.com/labenz

LinkedIn: https://linkedin.com/in/nathanlabenz/

Youtube: https://youtube.com/@CognitiveRevolutionPodcast

Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431

Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Vlad Tenev and Tudor Achim from Harmonic explain how they built Aristotle, an AI system that reaches International Mathematical Olympiad gold-medal performance using formally verified Lean proofs. They unpack the architecture behind mathematical superintelligence, including Monte Carlo Tree Search, lemma guessing, and specialized geometry modules. The conversation explores how verifiable reasoning could harden mission-critical software, reshape mathematical practice, and lead to trustworthy superintelligent systems by 2030.

Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot
Sponsors:

Claude:
Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr

Framer:
Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive

Blitzy:
Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com

Tasklet:
Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

CHAPTERS:

(00:00) About the Episode

(04:58) Math as reasoning (Part 1)

(15:22) Sponsors: Claude | Framer

(18:51) Math as reasoning (Part 2)

(18:51) Inside the Lean language

(27:51) Lean intuition and MathLib (Part 1)

(34:08) Sponsors: Blitzy | Tasklet

(37:08) Lean intuition and MathLib (Part 2)

(38:47) Inside Aristotle's architecture

(48:33) Scope, boundaries, and applications

(54:37) Training, taste, and interpretability

(01:08:18) Formal math and software

(01:16:50) Limits, entropy, and roadmap

(01:25:24) 2030 vision and safety

(01:33:38) Outro

PRODUCED BY:

https://aipodcast.ing

Abhi Mahajan (@owlposting) explains how AI is reshaping biology and medicine, including foundation models to predict cancer treatment response and why he’s both skeptical and optimistic about current results. Helen Toner unpacks CSET’s “When AI Builds AI” report and why automated AI R&D is a major source of strategic surprise. Jeremie Harris then explores our lack of control over superhuman AI systems, fragile US–China coordination, and how to maintain situational awareness in a rapidly shifting landscape.

Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot

LINKS:

Abhi Mahajan's Owl Posting site

Heuristics for lab robotics article


Deep Research on Noetik AI

Sponsors:

GovAI:

GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI.  GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 22 February 2026. Apply at: https://www.governance.ai/opportunities

Blitzy:

Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com

Tasklet:

Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

Serval:

Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive

Claude

Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at ⁠⁠https://claude.ai/tcr⁠

PRODUCED BY:

https://aipodcast.ing

Part 1 of this live special dives into AI for Science, U.S. AI policy, and the behavior of AI agents in open-ended environments. James Zou explains how interpretability and virtual labs of AI agents can accelerate scientific discovery. Sam Hammond assesses the Biden administration’s AI policy, U.S.–Gulf AI deals, and the odds current AIs are conscious. Shoshannah Tekofsky shares insights from studying agent performance and emergent behavior in the AI Village.

Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot

LINKS:

Model human wellness project doc

AI Village 2025 findings report

Sponsors:

GovAI:

GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI.  GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 22 February 2026. Apply at: https://www.governance.ai/opportunities

Blitzy:

Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com

Tasklet:

Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

Serval:

Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive

Claude

Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at ⁠⁠https://claude.ai/tcr⁠

PRODUCED BY:

https://aipodcast.ing