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The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey
The Human Upgrade: Biohacking for Longevity & Performance
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5 de 1378
  • Tom Cruise’s Secret FEAR Hack (+ Stress Biohacks for Longevity) : 1329
    If you’ve ever felt crushed by stress or trapped by fear, this episode gives you the science and strategies to break free. You’ll learn how Olympic-level coaching can rewire your brain for resilience, unlock peak human performance, and extend your longevity through proven biohacking tools. Watch the video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jim Murphy, a former professional baseball player turned Olympic coach and now bestselling author of Inner Excellence. Jim has spent decades training world-class athletes and high performers to master their mindset, expand neuroplasticity, and build the courage to thrive under pressure. His work blends psychology, functional medicine, and elite coaching to help people overcome fear, reframe failure, and step into their highest potential. Together, they explore the inner game of stress mastery: why fear lives in your mitochondria, how shame and guilt sabotage performance, and how to turn setbacks into resilience. They also discuss supplements that improve metabolism, why childlike wonder fuels longevity, and how to use practical biohacking to cultivate courage. This is essential listening for anyone serious about hacking fear, upgrading resilience, and living the smarter not harder way. Whether you’re chasing athletic greatness, leading at the highest level, or just seeking more freedom in daily life, these strategies show you how to unlock love over fear and achieve lasting longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: inner excellence, Jim Murphy, Olympic coach, fear hacking, stress mastery, resilience training, courage mindset, shame vs guilt, brain optimization, neuroplasticity, mitochondria stress, childlike wonder, longevity habits, emotional resilience, high performance, mindset coaching, presence training, love over fear, functional medicine, stress recovery, AJ Brown, AJ Brown book, Eagles football player book, NFL sidelines book Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Jim’s Website: https://innerexcellence.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:30 — Intro3:10 — Subconscious Mind and Fear4:36 — Purpose Beyond Results6:38 — Writing Inner Excellence10:16 — Redefining Mental Toughness14:11 — Guilt and Shame18:24 — Embracing Fear and Challenge23:50 — Teaching Kids and Modeling Behavior31:44 — Childhood Programming and Performance45:59 — Living Fully, Ready to Die??:?? — Maintaining Childlike WonderSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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  • BONUS: How To Reverse Testosterone Decline After 40 (Biohacking Tips) : 1328
    Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sabotaging your hormones. Want results? Start here.Chapters:0:00 – Introduction1:40 – The Lie About Aging and Testosterone2:49 – What’s Desatroying Your Testosterone Daily3:42 – How Your Cells Actually Make Testosterone4:58 – Why Diet is Step One (and What to Eat)7:08 – The Most Underrated T Booster8:38 – The Truth About Light and Hormones14:40 – How to Fix ItGet Your Oral Testosterone Here: http://www.LiveThrive.co/asprey Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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  • Eat THESE Anti-Aging Mushrooms to Live Longer (Paul Stamets) : 1327
    Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You’ll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You’ll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion’s mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion’s mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20’ for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am… • Paul Stamets’ Website: https://hostdefense.com/ Thank you to our sponsors! • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion’s Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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  • MIT Neuroscientist: The Ultimate Nootropic For Memory : 1326
    Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with neuroscientist and physician Dr. Tony Nader, the global leader of the Transcendental Meditation movement. With an MD and PhD from MIT and Harvard, Dr. Nader bridges hard science with ancient wisdom, showing how TM measurably changes brainwaves, boosts mitochondria, and even slows biological aging. His research connects meditation to reduced stress, faster reaction time, and improved memory, giving listeners cutting-edge tools for smarter not harder living. You’ll Learn: • How Transcendental Meditation induces high-coherence alpha brain states that improve clarity, focus, and resilience • Why TM increases blood flow to the prefrontal cortex and supports memory, decision-making, and creativity • How meditation measurably reduces biological age by 5–10 years through stress reduction and physiological balance • Why reaction time and situational awareness improve immediately after meditation — even used by fighter pilots • How TM differs from mindfulness or concentration practices at the brainwave level (alpha vs. theta vs. gamma) Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Transcendental Meditation benefits, Tony Nader MIT neuroscientist, TM brainwaves alpha coherence, Meditation and neuroplasticity, Default mode network meditation, Meditation and mitochondria, TM and biological age, Consciousness and quantum field theory, Meditation vs psychedelics, Meditation and intuition training, Meditation and dopamine, TM reaction time studies, Hippocampus meditation memory, TM and functional medicine, Meditation and metabolism, Meditation and PTSD recovery, TM for sleep optimization, Meditation and fasting stack, TM and human performance, Meditation and longevity research Thank you to our sponsors! Business of Biohacking Summit | Apply to The Business of Biohacking Summit https://businessofbiohacking.com/. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Tony’s Website: https://drtonynader.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:47 — Intro 2:57 — Transcendental Meditation 3:56 — States of Consciousness 10:16 — Brainwaves & Practice 18:35 — Science Bias 38:07 — Mind & Reality 50:32 — Psychedelics & TM 54:29 — Brain & Body Effects 59:31 — Daily Practice 1:02:43 — Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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  • How To Deal With The Fear Of Death (Ethics Of Longevity) : 1325
    Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Suzanne O’Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it’s too late. Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You’ll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. You’ll Learn: • Why fear of death silently undermines health, performance, and human potential • How forgiveness and gratitude rewire neuroplasticity and boost brain optimization • What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm • How unresolved trauma shows up as physical pain and disease at the end of life Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care Thank you to our sponsors! ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Suzanne’s Website: https://suzannebobrien.com/ • Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com• Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:05 — Introduction 03:13 — End-of-Life Choices 09:50 — Forgiveness & Suffering 15:46 — Advice to Younger Self 20:00 — What Makes a Good Death 23:00 — Hospice Stories & Mystical Experiences 33:05 — The Good Death Defined 41:01 — Meaning & Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
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