202 episodios
200. That's One Cell of a Machine: Jason Kelly of Gingko Automates Labs to Accelerate Discovery
25/09/2026 | 1 h 28 minFor the 200th episode of Grow Everything, Karl Schmieder and Erum Azeez Khan talk with Jason Kelly, co-founder and CEO of Ginkgo Bioworks and former chair of the US National Security Commission on Emerging Biotechnology, about why biology is still so hard to engineer. Jason explains why a cell is the only coded substrate we have besides a computer, why the real bottleneck is tooling rather than ideas, and why Ginkgo moved from royalty based research partnerships to selling robotic hardware and lab data as a service. Using a subway, car and Waymo analogy, he separates automation from autonomy and makes the case for replacing the manual lab bench, which eats roughly 97 percent of research spending while running 40 hours out of 168. He walks through Ginkgo's Boston system of 105 robots running 24/7, new autonomous labs for MIT, Caltech, Northwestern and the University of Maryland, and the OpenAI project where GPT-5 ran 30,000 experiments a week and beat state of the art in cell free protein synthesis by 40 percent. He also lays out the policy stakes as drug discovery shifts to China, and why the day biology becomes predictably easier to engineer, biotech gets bigger than tech.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
(00:00:00) A cell is a machine that can do a million other things
(00:07:00) AI data centers, contamination, and the waste to value opportunity
(00:14:00) Biosecurity, guardrails, and who is accountable for AI in biology
(00:21:00) Ginkgo's mission: programming a computer you did not design
(00:28:00) Why Ginkgo reset its business model from royalties to tools and data
(00:34:00) Subway, car, Waymo: what an autonomous lab actually means
(00:41:00) Inside Nebula: 105 robots, 24/7 lab work, and autonomous labs for MIT and Caltech
(00:47:00) The end of experimental scarcity and what scientists do next
(00:54:00) Offshoring biotech to China and the policy fix Jason wants
(01:01:00) Simulating cells, Moore's law for biology, and the markets beyond pharma
Links and Resources:
Gingko Bioworks
Gingko Bioworks - Automation product
Jason Kelly linkedin
Ginkgo Bioworks Joins ARPA-H GIVE Program to Build Autonomous Manufacturing System for Individualized RNA Medicines
National Security Commission on Emerging Biotech
Singapore is building supercomputer that runs on human brain cells
Water in Wyoming data center contaminated with cupriavidus gilardii
112. The Baked-In Future of Science: Nick Edwards on Potato AI’s Quest to Become Your AI Scientist
5. Dreaming in Biology: Tales from the Ginkgo Bioworks Studio
50. The Dye-Hard Innovator: Natsai Chieza Designs Change for the Fashion Industry and the World
Topics Covered:
autonomous labs, laboratory robotics, AI in biotechnology, synthetic biology, bioengineering, biological automation, data as a service, biotech infrastructure, cell engineering, programmable biology
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media199. Space, the Final Fermenter: Mario Maggio Brews Biology in Orbit with Ambrosia Space
18/09/2026 | 49 minBiology may be the most important technology we take off planet, and Mario Maggio is building the hardware to prove it. The founder and CEO of Ambrosia Space joins Erum Azeez Khan and Karl Schmieder to explain why space bioprocessing has been stuck at 10 to 20 milliliters while bench scientists on Earth work at 250 milliliters and beyond, and what changes when a two and a half liter fed batch bioreactor with pH, dissolved oxygen, and total cell density sensors finally flies. Mario traces his path from aerospace propulsion and the Nova C lunar lander at Intuitive Machines to life support systems at Paragon and Axiom Space, and the realization that biology is the best CO2 scrubber, oxygen source, and chemical factory available for long duration missions where petroleum, farms, and easy resupply do not exist. The conversation digs into the engineering reality of fluids and gas in microgravity, why glass and ceramics never fly, the stainless steel and aluminum builds that replace them, the intentional and unintentional bacteria that come with building a bioreactor from scratch, and the NASA TechLeap winning CellSep continuous flow centrifuge that carries cells and secreted products into downstream processing without gravity. Mario also lays out the near term commercial case, from protein crystallization and monoclonal antibodies that behave differently in orbit to biofuels, vitamin production, medicines, and the big silver tanks that will feed astronauts because there will be no farms or cattle. He offers a candid read on artificial gravity gradients, why the Moon matters for building large vehicles in space, and why the same hardware that grows yeast for beer on Mars becomes the root of better biomanufacturing on Earth. Erum and Karl open with field notes from Bio Innovations North America in Omaha, including Midwest feedstock advantage, consortia momentum, the 30 percent of cost hiding in downstream processing, and why Smucker and Mars are actively scouting biotech innovators.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
(00:00:00) Why Biology Is the Best Commercial Case for Space
(00:04:52) Bio Innovations North America and the Midwest Bioeconomy
(00:07:21) Why Smucker and Mars Are Scouting Biotech Innovators
(00:11:42) Inside Ambrosia Space: Bioreactors Built for Orbit
(00:15:24) Scaling Past 150 Milliliters: Space Biology's Volume Problem
(00:18:12) Stainless Steel, Leaks, and Why Glass Never Flies
(00:21:36) NASA TechLeap and the CellSep Continuous Flow Centrifuge
(00:26:08) Protein Crystals and Monoclonal Antibodies Made in Microgravity
(00:31:22) Artificial Gravity, Lunar Bases, and Closing the Loop on Life Support
(00:36:12) Quick Fire: Space Food Reality, HAL, and Biologics in Orbit
Links and Resources:
Mario Maggio
Ambrosia Space LinkedIn
Ambrosia Space
111. Space Genes and Subway Scenes: Chris Mason on Planning Life’s Next Big Leap
93. Houston, We Have a Protocol: NASA's Kate Rubins on Biotech in Space
187. One Small Step for a Microbe: Lynn Rothschild’s Leap from Astrobiology to Bioengineering at NASA
185. Brick Happens: Chris Maurer of Redhouse Studio Redesigns Remote Living for Earth and Mars
152. Crystals in the Cosmos: Varda Rewrites Drug Formulation in Microgravity
Grow Everything LinkedIn
Topics Covered:
space biomanufacturing, Ambrosia Space, orbital bioreactors, microgravity biotechnology
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media198. A Grain of Truth: Chef Pierre Thiam Scaled Fonio Without Losing Its Roots
11/09/2026 | 1 h 2 minChef and entrepreneur Pierre Thiam joins Grow Everything to explain how fonio, a resilient ancient grain from West Africa, can become a platform for biodiversity, regenerative agriculture, food security, and farmer prosperity. Pierre traces his journey from studying physics and chemistry to discovering the kitchen as a larger system connecting culture, health, ecology, and economics. He shares why fonio is nutritionally dense, gluten free, drought resistant, fast cooking, and versatile, as well as how Yolélé is building aggregation centers and modern processing infrastructure while keeping cultivation knowledge and ownership with smallholder farming communities. The conversation explores how biotechnology can complement biodiversity, why flavor must lead climate friendly food adoption, how underutilized crops can create clean label ingredients and new commercial markets, and why food can serve as a powerful tool for diplomacy and cultural understanding. For founders, scientists, investors, and builders in the bioeconomy, Pierre offers a human centered model of innovation that begins with nature, respects generational knowledge, and uses technology to unlock solutions that have been in front of us all along.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
(00:00:00) Why flavor must lead sustainable food adoption
(00:07:00) Artificial intelligence for science and protein design
(00:14:00) Pierre Thiam connects cooking, chemistry, culture, and diplomacy
(00:21:00) What fonio tastes like and why chefs love its versatility
(00:28:00) Scaling fonio through farmer centered supply chains and global markets
(00:35:00) Human centered design for West African farming communities
(00:42:00) Delicious first: the strategy behind climate friendly food adoption
(00:49:00) Biodiversity, forgotten crops, and the future of food security
(00:56:00) How biotechnology and local knowledge can work together
(01:02:00) Building healthier diets and stronger farming communities
Links and Resources:
Chef Pierre Thiam
Teranga - Senegalese Restaurant
Yolélé Foods
The Fonio Cookbook
Chief Pierre Thiam Instagram
197. What’s in Your Cart? A Grocery Store Walkthrough of Next-Gen Food Innovation
196. Beyond the Red Tape: Greg Jaffe on Policy as an Accelerator for Bio-Innovation
New Evidence points to ‘Ghost DNA’
Claude opens 10,000 free seats to scientists
David Kong's class - How To Grow Almost Anything
BioInnovations Events - For 25% off use code: Grow Everything
Grow Everything LinkedIn
Topics Covered:
Fonio, West African cuisine, sustainable food systems, regenerative agriculture, food biodiversity, underutilized crops, food diplomacy, Bambara groundnuts, climate-resilient crops, Yolélé
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media197. What’s in Your Cart? A Grocery Store Walkthrough of Next-Gen Food Innovation
04/09/2026 | 15 minFood technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episode, Erum Azeez and Karl Schmieder visit six stops across the grocery store to explore sweet proteins from Oobli, fermentation derived colorants from MycoFutures and Chromologics, the antioxidant rich purple tomato from Norfolk Healthy Produce, fungi based proteins from The Better Meat Co. and MyForest Foods, sargassum derived ingredients from Origin by Ocean, and the hard commercial work of getting emerging products onto retail shelves. For founders, scientists, investors, and builders across synthetic biology and sustainable materials, the central lesson is clear: fermentation is manufacturing, environmental problems can become valuable feedstocks, and biology wins when performance, taste, branding, and price are better for the customer.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
(00:00:00) Food technology innovations hidden across the grocery store
(00:01:57) Why fermentation should be understood as manufacturing
(00:03:02) Oobli sweet proteins replace sugar with tiny amounts of protein
(00:04:35) Fermentation creates powerful natural colors for food brands
(00:06:20) The purple tomato brings biotechnology into the produce aisle
(00:08:11) The Better Meat Co. grows nutrient rich mycoprotein in bioreactors
(00:09:54) MyForest Foods turns oyster mushroom mycelium into bacon
(00:11:15) Origin by Ocean transforms invasive sargassum into useful ingredients
(00:12:34) Startup CPG explains what gets emerging brands onto shelves
(00:13:50) Why biology must compete on taste, price, branding, and performance
Links and Resources:
22. Sweet Dreams Are Made of Proteins: Oobli's Ali Wing
180. Fungi in Full Color: Ricky Cassini Reimagines Dye at Michroma
181. Can Hue Believe It? Gerit Tolborg’s Quest for Pure Color at Chromologics
33. Purple Reign, A Purple Tomato with a Genetic Twist, Nathan Pumplin of Norfolk Healthy Produce
157. (Thanksgiving Replay) Meat the Future: How Paul Shapiro is Brewing Superfoods at Better Meat Co.
126. Sizzling Success: Eben Bayer of MyForest Foods on Scaling Mycelium Magic
175. Seaweed Is the New Oil: Mari Granström Builds Origin by Ocean
167. From Scrappy to Scalable: Daniel Scharff Grows Startup CPG
BioInnovations Events - For 25% off use code: Grow Everything
Grow Everything LinkedIn
Topics Covered:
Food technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episode
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media196. Beyond the Red Tape: Greg Jaffe on Policy as an Accelerator for Bio-Innovation
28/08/2026 | 55 minBiotech is moving fast, but regulation, public trust, and infrastructure still shape how quickly new ideas reach the market. In this episode of Grow Everything, Greg Jaffe joins Karl Schmieder to explore the regulatory future of the bioeconomy, drawing on Greg’s experience in environmental law, consumer advocacy, and as the USDA’s chief regulatory officer. They discuss why founders need to think about regulatory strategy early, how production methods, product claims, and intended use can dramatically change the path through agencies like USDA, EPA, and FDA, and why clear oversight can help build the trust emerging technologies need to scale. Greg and Karl also examine the regional nature of biomanufacturing, the importance of rural infrastructure and local partnerships, and why the future of the bioeconomy will require coordinated policy, stronger market demand, international access, and regulatory pathways that support innovation while protecting public confidence.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
(00:00:00) Intro: Moderna cancer vaccine news, Sargassum in Miami, and K18’s viral hairball activation
(00:13:00) Greg Jaffe’s path from environmental law to biotech policy
(00:16:30) Why the coordinated framework for biotechnology still matters
(00:20:00) What biotech startups need to understand about USDA, EPA, and FDA
(00:25:15) How claims, intent, and language can change a regulatory pathway
(00:28:15) Why public trust is essential for biomanufactured food and biotech products
(00:31:30) How biotech regulation differs in the United States, Africa, and Southeast Asia
(00:35:20) Why biomass and biomanufacturing are inherently local
(00:38:00) Which bio based sectors may be ready to scale first
(00:42:20) The role federal policy can play in making bio based products the default
Links and Resources:
Greg Jaffe
Jaffe Policy Consulting LLC
U.S. Department of Agriculture
BioPreferred Program - USDA
What is it like to be a cucumber? - Mike Levin
The Merck/Moderna cancer vaccine: How does it work and what are potential barriers to wide use?
Miami faces worsening seaweed problem as piles of algae wash up on beaches
SPOTTED K18 Hair: a giant hairball rolling across NYC
BioInnovations Events - For 25% off use code: Grow Everything
Grow Everything LinkedIn
Topics Covered:
USDA regulation, FDA food regulation, GRAS process, cultivated meat regulation, precision fermentation, food safety policy, bioeconomy policy, agricultural biotechnology, ultra-processed foods
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media
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Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.
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