Grow Everything Biotech Podcast

• Live at BioFab Fair. Celebrating 150 Episodes!

  In this special 150th episode of Grow Everything, Erum and Karl broadcast live from the BioFab Fair 2025 in London. They explore the innovative world of biology as technology with special guests Elliot Roth and Amanda (from Mothership Materials), discussing community biotech labs, biopunk culture, and sustainable feedstocks for the bioeconomy.Episode Links:Gozen Lunaform video. Wow! - https://vimeo.com/1061047875Biopunk Lab - https://biopunklab.com/Pacagen - https://pacagen.com/Deep Science Ventures - https://www.deepscienceventures.com/Mothership Materials - https://www.mothershipmaterials.com/Topics Covered:Biofabricate, Biofab Fair, live recording, 150 episodes, biomaterials, textiles, fabrics, furniture, community biotech, biopunk, cultivation, microbes, bioprocessing, biomanufacturing, waste agricultureHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter/ LinkedIn / Youtube/ Grow EverythingChapters:00:00:00 - Introduction to BioFab Fair 202500:01:43 - Reflections on day one of BioFab Fair00:06:00 - Interview with Elliot Roth on Biopunk culture00:07:00 - From hacker to punk: Redefining biotech development00:10:00 - The rise of community bio labs and why they're having a moment00:12:00 - Missing small business biotech and problems with VC funding00:14:00 - Weird biotech innovations around the world00:20:00 - Global tour insights and medical tourism observations00:24:00 - Call to action for Biopunk movement00:27:00 - Interview with Amanda from Mothership Materials00:28:00 - Breakthrough technology for agricultural waste processing00:30:00 - The importance of glucose for scaling biomanufacturing00:34:00 - Introducing "Microbe Munch" - specialized sugar for microbes00:38:00 - The future of distributed biomanufacturing

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• Beyond Capital: Phil Morle of Main Sequence Ventures on Collaboration as the New Competitive Edge

  This episode explores the journey from scientific breakthrough to scalable industrial implementation. Phil Morle — partner at Main Sequence and co‑founder of Pollenizer — explains how strategic off‑takes generate market pull, the reasons nylon recycling advanced faster than PET, and the orchestration techniques required to progress from First-Of-A-Kind (FOAK) to Next-Of-A-Kind (NOAK) facilities. The conversation covers practical aspects of costs, partnership development, policy incentives, and industrial realities, including Phil's pragmatic test: "if it doesn't need a forklift, it's not relevant."Chapters:- 00:00:00 – Intro and producer mindset- 00:06:53 – Orchestration and Samsara origin story- 00:07:53 – Market pull with Woolworths and ANU enzymes- 00:11:12 – Why nylon before PET- 00:12:12 – Offtake vs. equity checks- 00:31:40 – Industrial reality: the forklift test- 00:33:56 – Samsara's infinite-recycling facility- 00:34:33 – Biomanufacturing as infrastructure- 00:40:25 – FOAK to NOAK playbooks- 00:55:00 – Cauldron's HyperFermentation infrastructureEpisode Links:- Main Sequence Ventures - https://www.mseq.vc/- Lululemon & Samsara deal - https://corporate.lululemon.com/media/our-stories/2025/lululemon-and-samsara-eco-announce-10-year-plan-to-advance-recycled-material-portfolio)- Future of Fungi Awards - https://www.futureisfungi.org/- **Michele Stansfield Episode** - https://creators.spotify.com/pod/profile/messaginglab/episodes/85--Always-Be-Brewing-Continuous-Fermentation-with-Cauldrons-Michele-Stansfield-e2lu3kdTopics Covered:venture capital, ecosystem orchestration, biotech, australian businessHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram/Twitter/LinkedIn/Youtube/Grow Everything

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• 148: "Wrinkle in Time? OneSkin’s Alessandra Zonari Says Not Anymore”

  In this episode of Grow Everything, hosts Karl Schmieder and Erum Azeez sit down with Dr. Alessandra Zonari, co-founder and Chief Scientific Officer at OneSkin. Alessandra shares her personal journey from Brazil to biotech, driven by a mission to transform how we think about aging. She explains the science of cellular senescence, the discovery of the groundbreaking OS-1 peptide, and why skin is more than a beauty surface—it’s a window into systemic health and longevity. Listeners will hear candid insights into the challenges of translating biotech discoveries into consumer products, the importance of radical transparency in science communication, and where peptides and personalized skincare fit into the future of the longevity movement. This is a must-listen for anyone passionate about synthetic biology, sustainable innovation, and the science of healthy agingGrow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Welcome to Grow Everything Podcast(00:00:18) London's Bio Fab Fair Recap(00:02:34) Biotech's Bottom Line Impact(00:05:49) Pharma's Path to Consumer Products(00:08:00) The Accidental Discovery of Splenda(00:09:26) Meet Dr. Alessandra Zonari(00:10:54) A Scientist's Personal Mission(00:13:15) "Zombie Cells" and Skin Aging(00:16:30) Longevity Science vs. Marketing(00:18:28) The Hunt for the OS-01 Peptide(00:21:39) The Five-Year Path to Market(00:22:49) Science-First Communication(00:28:21) The Challenge of Going to Market(00:31:16) Communicating to Beauty vs. Biotech(00:33:45) The Future: Personalized Peptides(00:36:24) Why Science Storytelling Fails(00:38:42) Advice for Scientist-Founders(00:40:00) Peptide vs. SPF(00:40:42) Busting the Biggest Aging Myth(00:41:11) The Future of Personalized Aging(00:43:33) Why Aging is "Excited"(00:44:15) Actress or Astronaut(00:46:17) Peptides as "Cell Messages"Episode Links:Julie wolf episodeOneSkinTopics Covered: skincare, cellular senescence, peptides, OneSkin, skin health, anti aging  Have a question or comment? Message us here:Text or Call (804) 505-5553

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• 147: "Shhh…They’re Talking: Holoclara's Dr. Andrea Choe Tunes Into Worm Signals for Health”

  What if we could treat debilitating diseases by listening in on the "secret, invisible language" of worms? In this groundbreaking episode, we talk with Dr. Andrea Choe, Co-Founder and CEO of Holoclara, who uncovered a "universal worm language" used for hundreds of millions of years. Dr. Choe reveals how our modern "aggressive hygiene routine" removed the worms we co-evolved with, leading to a rise in allergic and autoimmune diseases. Discover how her team is pioneering a new class of safe, orally available therapies by synthesizing worm-derived molecules that "rebalance" our immune systems and have already blocked disease in animal models. This is a fascinating journey from a fundamental discovery in evolutionary biology to the cutting edge of biotech innovation.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Welcome to Grow Everything Podcast(00:00:18) NYC Biotech and Climate Week Recap(00:08:43) Science News: Comets and Octopuses(00:15:17) Meet Dr. Andrea Choe(00:15:52) From Researcher to Founder: The Call to Action(00:17:25) Discovering the Universal "Worm Language"(00:25:11) Connecting Worm Secretions to Therapeutics(00:29:49) How Modern Hygiene Created an Immune Imbalance(00:34:35) Navigating the Hurdles of Natural Medicine(00:38:50) Holoclara's Mission to Treat Eosinophilic Esophagitis (EoE)(00:42:25) Holoclara's Phase 1 Safety and Trial Results(00:51:03) Moonshot Vision: A "Worm Atlas" of Molecules(00:52:28) The Strategy for Patenting Natural Molecules(00:54:33) Worm Superpowers & Immune Myths(00:58:25) Reflecting on Nature's Untapped Answers(01:02:41) Coming Up on Grow EverythingEpisode Links:HoloclaraHuman Genome project Diary of a worm - Doreen Cronin Wildlife of Our Bodies - Rob DunnSuzanne Lee  Ep Glennis Mehra EpEllen Jorgensen EpInnolabsNucleate Biolabs NYU LangoneGenspaceBiotech Without Borders Newlab Climate Week Event - sign up and get tickets now! Interstellar Comet Moving Through Our Solar SystemTopics Covered: immune system, biotherapeutics, worms, evolution, helminthic immunomodulation, medicine, pharmaceuticals  Have a question or comment? Message us here:Text or Call (804) 505-5553Instagram  / Twitter / LinkedIn / Youtube / Grow Everything

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• 146. Pump It Up: Benji Leibowitz on DAO-ing Science Differently

  In this episode of Grow Everything, hosts Karl Schmieder and Erum Azeez talk with Benji Leibowitz, Co-Founder of Pump Science, about what it really means to be “DAO-ing science differently.” From the early days of Molecule DAO to today’s crypto-native platform for funding longevity and nootropics research, Benji explains how decentralized science (DeSci) can rebuild healthcare and biotech from the ground up. By combining bonding curves, tokenized IP, and radical transparency with live-streamed worm and fly experiments, Pump Science is transforming science into an attention game that’s fast, fun, and open to everyone. Tune in to hear how DAO-driven models are unlocking underfunded areas like longevity, attracting crypto investors, and creating a new culture where research is not only transparent but also entertaining.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Welcome to the Grow Everything Podcast(00:00:49) Proposed U.S. budget cuts to research(00:01:59) How jargon fuels skepticism in science(00:02:25) China's bioeconomy surpassing U.S. in biotech investment(00:04:31) Rising gut imbalance in infants: My Baby Biome study(00:06:35) Billionaires investing heavily in longevity research(00:08:21) Wishing for more entertaining "fun" billionaires(00:10:26) Meet Benji(00:13:07) Rebuilding healthcare and biotech from scratch (DeSci)(00:15:15) From tokenizing biotech IP to Pump Science’s new model(00:18:09) Focusing on longevity to attract crypto investors(00:23:56) Optimizing experiments with C. elegans worms(00:27:47) A high-velocity "casino" model backed by real IP(00:33:18) Launching compound tokens on a bonding curve(00:36:36) Funding research through small trading fees(00:40:34) Gamifying research: rewarding top-performing compounds ("King of the Pill")(00:43:23) Using live streams for trust and funding transparency (DeSci)(00:46:35) "Fly races" as entertainment and a longevity indicator(00:48:56) Excitement for performance enhancement and nootropics (Pump Science)(00:50:14) Rapid-fire guest Q&A(00:51:32) Advice for newcomers to Pump Science(00:53:06) Reflecting on the guest's model for funding science(00:55:31) DeSci’s potential to build a parallel healthcare systemEpisode Links:Advocate for Science - Contact Your CongresspersonPump.ScienceMoleculeDAODeSci 101 EpisodeLaura Miniquini Episode Michael Fisher EpisodeJocelynn Pearl EpisodeAlbert Anis EpisodeStephanie Culler, Persephone EpMomo and Guru - Viome EpisodeMap of Longevity Companies Attracting Investor InterestThe Gut Microbiome Protects Infants from DisasesBioFab Fair - Use promo code: GROW10 for a discount to attend! Topics Covered: Decentralized science, DAO, longevity, open science, crypto science   Have a question or comment? Message us here:Text or Call (804) 505-5553Instagram  / Twitter / LinkedIn / Youtube / Grow Everything

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