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For the first time in nearly 70 years, it looks like there may be major political changes afoot in Cuba — driven by the United States.
The Trump administration has been ratcheting up pressure on the island, including by imposing an oil embargo that is strangling the country's energy supplies. On Monday, March 16, Cuba experienced a complete collapse of its electric grid, triggering a nationwide blackout. Meanwhile, Cuba's erstwhile major patron was Venezuela, which, since the ouster of Maduro, no longer provides the support on which Havana once relied. Recent reporting also indicates that Washington and Havana are now engaged in direct talks, even as the Trump administration is explicitly seeking the ouster of President Miguel Díaz-Canel. Trump has also publicly suggested he could "take" Cuba.
So will Cuba go the way of Venezuela? What role does the U.S. war in Iran play in Washington's policy toward Cuba? And might the Cuban regime survive after all?
My interview guest today, James Bosworth, answers these questions and more. He writes the Latin America Risk Report on Substack, and we kick off with a brief overview of seven decades of U.S.-Cuba relations before having a longer conversation about where things stand today — and where they may be headed.
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Earlier last last week, he United Nations reported that around 300,000 Lebanese had been displaced since Israel opened a new front in southern Lebanon amid this widening regional conflict. Yesterday, that figure surged to more than 800,000 people forced from their homes in just a matter of days.
Lebanon is where the humanitarian crisis stemming from the Iran war is most urgent at the moment—but the fallout is rapidly spreading across the region. In Gaza, humanitarian aid has dropped dramatically following Israel's decision to close a major crossing. Pakistan is bracing for refugees even as it is in the midst of its own war with the Taliban, and in Iran itself, more than 3 million people are reportedly displaced.
But according to my guest today, the impact of this conflict on some of the world's most vulnerable people will be felt far beyond the region. Scott Paul is the Director of Peace and Security at Oxfam America. We begin by discussing the various crises this war has sparked across the region before turning to a broader conversation about the impact this conflict will have on humanitarian operations worldwide.
In short, the ability of local and international humanitarian organizations to meet the basic needs of millions of people around the world has just become substantially more difficult because of this war.
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Today's episode is produced in partnership with the Global Challenges Foundation. The Foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. Global Challenges Foundation's 2026 Global Catastrophic Risks report outlines five of the biggest risks facing humanity today, including catastrophic climate change, the topic of this episode. You can find this report at globalchallenges.org/gcr-2026. 
Two of the authors of the chapter on catastrophic climate change are my guests today. Manjana Milkoreit is a researcher of earth systems governance at the University of Oslo. Eva Mineur is head of climate and sustainability at Global Challenges Foundation. 
We kick off by discussing what we mean by catastrophic climate change and examining examples of this phenomenon already underway around the world, before turning to a longer conversation about how to strengthen international cooperation and global governance to prevent catastrophic climate change—and the catastrophe it would entail.

We cover a lot of ground in this week's episode of To Save Us From Hell! There are two new entrants to the race to succeed António Guterres as the next UN Secretary-General; Cindy McCain announced she is stepping down as head of the World Food Programme, meaning there will soon be a vacancy at the top of one of the largest UN agencies—one typically led by an American; and we dissect a bizarre Security Council meeting earlier this week chaired by…Melania Trump. But we begin with an extended discussion of how the new war in Iran is impacting diplomacy at the United Nations—and what role the UN may play as this conflict evolves.
The full episode is immediately available after the fold for our paying subscribers. You can use the discount link to get 40% off a subscription, or, if you'd prefer, support Global Dispatches and To Save Us From Hell at full price.
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Things are obviously moving very fast in the Middle East. When I caught up with my guest today, Dalia Dassa Kaye, the war was in its second day. Bombings in Iran and throughout the region continued at a rapid clip, and there was little sense of when, if, or how it might end.
Regular listeners of the show are no doubt familiar with Dalia Dassa Kaye. She is a senior fellow at the UCLA Burkle Center for International Relations and the author of a new book on U.S.–Iran relations, Enduring Hostility: The Making of America's Iran Policy. She has researched and written extensively about escalatory dynamics in the region—how Iran, Israel, the United States, and Gulf countries may respond to being attacked. Now that this dynamic is clearly underway, I thought it would be useful to get her perspective on what we are seeing unfold.
We kick off by discussing why the United States and Israel launched this war, given that Trump has never really articulated his motivations as the U.S. moved massive military assets to the region. We then discuss where this may head—and what might inspire de-escalation in the near future.
This conversation will give you useful context as this crisis continues to develop.
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