Stronger by Design for Women with Michelle MacDonald

What if the menopause industry isn't failing women but instead  it's deliberately targeting them?
Michelle MacDonald sits down with scientist, physician, and Selfority founder Dr. Sarah Berg for a conversation that pulls back the curtain on how a $15 trillion industry is built on the gap between what women need and what medicine has historically given them. 
Together they unpack why midlife women have become the most targeted consumer demographic in wellness, how the "natural" hormone narrative that exploded after the 2002 WHI study opened the door for an entire compounding market, and why so many women are making major health decisions at 3am while sleep deprived and algorithmically cornered. 
They also dig into the science of the placebo effect including why supplement companies deliberately build their packaging around the same 4 to 8 week window that research shows produces maximum placebo response and what it means to advocate for yourself in a space designed to exploit your vulnerability. 
This is an episode for every woman who has ever wanted to optimize her health and found herself wondering whether she's being helped or just sold to.

Favorite Moments
1:35 Why Women Over 50 Are a $15 Trillion Target
3:21 The Group Text Is the New MLM
7:41 How the 2002 Hormone Scare Built the Compounding Market
9:42 Bioidentical Hormones: What the Word Actually Means
13:34 The Placebo Study That Should Make You Rethink Every Supplement You've Bought
15:27 Why Supplement Packaging Says "Wait 4 to 8 Weeks" and It's Not an Accident
17:38 The 2002 Sham Knee Surgery That Proves the Brain Is the Most Powerful Drug We Have
24:44 The DUTCH Test: What It Is, What It Can't Do, and Why It Often Leads to a Supplement Stack
29:38 Drunk Buying at 3am: Sleep Deprivation, Algorithms, and the Menopause Marketing Machine
35:32 Why Your Jeans Stopped Fitting - The Estrogen & Visceral Fat Connection
41:36 Skinny Check vs. Frailty Check: The Reframe Women Actually Need
46:34 What's Coming: The $24 Billion Menopause Research Bill and Medical School Curriculum Change

"They're taking it because they're getting humbled relentlessly by the story that their bodies are broken. And so they're not even looking at the big levers." ~ Dr. Sarah Berg

GUEST: DR. SARAH BERG
Founder, Selfority | Principal Scientist, Unbiased Science
Instagram: https://www.instagram.com/selfority/
Website: https://www.selfority.com/
Dr. Sarah Berg is a physician-scientist and fierce advocate for evidence-based communication in women's health. As a Principal Scientist with the Unbiased Science team, she brings clinical expertise and a sharp eye for predatory marketing to one of the most underserved areas in medicine. Through Selfority - a name she built to say "self priority" out loud - she is on a mission to make sure women have the information they actually need to make informed decisions about their health, not just the information someone is trying to sell them.

About Michelle:
Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.
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Stronger by Design Podcast
🎙️ Spotify: https://open.spotify.com/show/7uljSBX7oSNQWhDVutk29m
🎙️ Apple Podcasts: https://podcasts.apple.com/us/podcast/stronger-by-design-for-women-with-michelle-macdonald/id1677831398
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Connect with Michelle:
📸 Instagram: https://www.instagram.com/michellemacdonaldofficial/
📘 Facebook: https://www.facebook.com/michelle.macdonald.yhhedonista
▶️ YouTube: https://www.youtube.com/@michellemacdonaldofficial
🔗 Website: https://www.michellemacdonaldofficial.com/

What if the peptide your favorite influencer is swearing by has never once been tested in a human clinical trial?
Michelle MacDonald sits down with drug development scientist Leigh Baxt, PhD  for a conversation that cuts straight through the wellness peptide industry.
Together they break down how drugs actually make it from an idea to FDA approval, why 99% of them never do, and what it means that the peptides flooding your social media feed are, in most cases, sitting at the very earliest stage of that process with almost no human data behind them. 
This episode digs deep into BPC-157 specifically, examining why the science raises serious red flags, and what informed consent actually sounds like when a clinician is promoting something with this little evidence. 
This information is essential listening for women who want to take charge of their health, cut through the marketing noise and make truly informed decisions.
Favorite Moments
1:57 The Staggering Failure Rates Behind Every Drug You've Ever Taken
3:07 From Idea to FDA Approval: What the Process Actually Looks Like
5:28 BPC-157: Why the Red Flags Are Hard to Ignore
12:49 Stacking Peptides & the Drug Interaction Problem Nobody Talks About
16:30 When Clinicians Become Marketers
22:21 How to Use ClinicalTrials.gov to Check the Evidence Yourself
28:22 The Patent Myth That Peptide Promoters Keep Repeating
"I want people to be informed. I want them to understand what data does and doesn't exist. Most importantly, I want them to be able to differentiate data from marketing — because even the most seasoned scientists can get sucked in." 

— Leigh Baxt, PhD
GUEST: LEIGH BAXT, PhD - DRUG DEVELOPMENT SCIENTIST

Instagram | LinkedIn
Leigh works in early-stage preclinical drug development, the phase where 90% of ideas fail before they ever reach a human. Her work focuses on understanding whether promising biological mechanisms can actually be turned into safe, effective therapeutics. She volunteers her expertise with the Unbiased Science team to help the public understand how medicines are made, why the vetting process matters, and how to tell the difference between data and marketing.
CONNECT WITH MICHELLE
Website | Instagram | YouTube | Facebook | X
About Michelle:
Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.

Where to Watch/Listen:
Website Apple Podcasts Spotify YouTube
Leave a rating for this podcast with one click.
Nothing in this video or podcast constitutes medical advice. Always consult a qualified healthcare professional before making changes to your health or fitness routine.

What if the reason your lifts, runs, or rotational power feel off has nothing to do with motivation—and everything to do with pelvic floor coordination?
Michelle MacDonald sits down with pelvic health and performance specialist Rachel Selman for a conversation that bridges the gap between rehab and real athletic training. Together, they explore how the pelvic floor functions in loaded movement, why Kegels alone are not enough, and how women…especially midlife female athletes, can progress from foundational control to strength, rotation, deceleration, and power. Rachel breaks down the role of breath, pressure, thoracic rotation, hip internal rotation, and movement coordination in a way that is practical, evidence-based, and immediately useful. This episode is especially valuable for women interested in Women’s Health and Fitness, a stronger Fitness Mindset, and long-term Personal Growth in how they train and move.

Favorite Moments
1:47 The Pelvic Floor Is a Dimmer Switch, Not an On/Off Button
6:00 "Strength Gives Permission to Soften"
19:57 The Four-Phase Progression: Control, Function, Strength, Power
36:13 Once a Month: The Pelvic Floor Check-In Protocol for Symptom-Free Athletes

"Strength gets permission to soften. If I strengthen a muscle that's overactive, what I actually notice is that it will follow by softening." – Dr. Rachel Selman

GUEST: DR. RACHEL SELMAN, PT, DPT, CERT-DN, CSCS, CPSS, TPI CERTIFIED
Website | Instagram | LinkedIn | Synthesis App
Full Guest Bio:
Dr. Rachel Selman is a pelvic health and performance specialist who helps women connect pelvic floor function to strength, movement, and athletic performance. Her work focuses on practical, evidence-informed strategies that go beyond traditional pelvic floor training, helping women improve coordination, stability, and confidence in everything from lifting and running to everyday life. She is known for making complex pelvic health concepts accessible and relevant for active women, coaches, and athletes.
CONNECT WITH MICHELLE
Website | Instagram | YouTube | Facebook | X
Full Michelle Bio:
Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.

Where to Watch/Listen:
Website Apple Podcasts Spotify YouTube
Leave a rating for this podcast with one click

Your shoulders are not invincible and waiting until something breaks is not a strategy !
Michelle MacDonald sits down with Dr. Patrick Denard, board-certified orthopedic surgeon and founder of the Oregon Shoulder Institute. This episode is for every woman who is serious about building strength and wants to keep training for life. Dr. Denard breaks down what damages women's shoulders, why 50% of people over 65 have a rotator cuff tear without knowing it, when physiotherapy is enough and when surgery is the smarter move, and the truth about PRP and stem cell therapies. You'll leave with the knowledge and permission to take radical ownership of your shoulder health before it's too late.
Favorite Moments
4:09 Why many women are arriving at their sixties with no muscle training history?
8:32 What training habits are silently destroying women's shoulders?
17:29 How do you catch shoulder warning signs before it's too late?
29:34  Dr. Denard explains what women must know about cortisone injections
40:11 Dr. Denard's top three must-dos for shoulder health over 40

"If you have the right mindset, good nutrition, and a good surgeon, your shoulders are going to be in a really good spot." - Dr. Patrick Denard
 
GUEST: DR. PATRICK DENARD, MD | BOARD-CERTIFIED ORTHOPEDIC SURGEON, SHOULDER SPECIALIST 
Website | Instagram | LinkedIn | Facebook | X | YouTube 
Full Guest Bio:
Dr. Patrick Denard is a board-certified orthopedic surgeon and founder of the Oregon Shoulder Institute, specializing exclusively in shoulder surgery and performing over 800 procedures a year. One of the highest-volume shoulder specialists in the country, he publishes extensively on rotator cuff repair and shoulder arthroplasty and lectures internationally on advanced techniques. He is the surgeon who performed Joan MacDonald's shoulder replacement, restoring her ability to train pain-free at nearly 80 — and he brings that same commitment to every active patient who refuses to let injury define the rest of their life. 
CONNECT WITH MICHELLE
Website | Instagram | YouTube | Facebook | X
Full Michelle Bio:
Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.
Where to Watch/Listen:
Website Apple Podcasts

What if the problem isn’t discipline, but outdated health advice?
Michelle MacDonald sits down with Dr. Gabrielle Lyon, board-certified physician and leading voice in muscle-centric medicine. Dr. Lyons explains why muscle, not weight, is the foundation of healthy aging for women. They cover protein targets, carb tolerance, type II muscle fibers, and why strength training matters for lifelong independence.

Favorite Moments
1:41 Muscle Is Agency, Not Just Fitness
7:10 Why Muscle-Centric Protein Guidelines Changed
35:56 How Muscle Determines Carbohydrate Tolerance
40:00 Type II Muscle Fibers: The Strength Women Lose First

“Muscle isn’t about fitness. It’s about agency.”- Dr. Gabrielle Lyon

GUEST: DR. GABRIELLE LYONS, BOARD-CERTIFIED PHYSICIAN SPECIALIZING IN MUSCLE HEALTH, AGING, AND LONGEVITY
Website | Instagram | LinkedIn | YouTube | The Forever Strong Playbook | TikTok
Full Guest Bio:
Dr. Gabrielle Lyon delivers science-backed strategies to help people build strength, energy, and resilience so they can perform at their best at work, home, and in life. Featured on Diary of a CEO, Huberman Lab, and the TEDx stage, she also hosts The Forever Strong Summit. A Wall Street Journal, USA Today, and New York Times best-selling author, Dr. Lyon is trusted by organizations including John Hancock, Keller Williams Realty, Shaklee, Parker Seminars, and Oprah Daily.
CONNECT WITH MICHELLE
Website | Instagram | YouTube | Facebook | X
Full Michelle Bio:
Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.
Where to Watch/Listen:
Website Apple Podcasts Spotify YouTube